I have the wrong rear wheel on my K100 (a later 16v item) which bolts up fine but the rim is offset to the left by about 25mm, I've never noticed any handling difference except maybe a little weirdness when running along white lines. Tyre wear appears unaffected. Thankfully, because it's shaft drive, MOT testers never think to check it I also went Germany one year and didn't check whether the tyre man had fitted the rear wheel straight, which he hadn't.. It was a good few notches out but again I never noticed! The chain didn't even make any extra noise, amazing what you can get away with.