I've been an Honda guy since my first bike and have no intentions to bulge from it.
The first bike I had was an Africa Twin, superb bike for learning, very forgiving and teaches you hoe to use the brakes adequately.
Then I had 2 VFR800. Really fun to ride, fast, comfortable for a sport tourer.
When I past the speedy Gonzales stage I went for a Pan European, heavy when you need to move it by hand but in my opinion, one of the best for long touring trips.
Because I want to use the bike for commute when the weather allows I got myself a Shadow 700, light good for trips around 100 miles, still good speed and handling.
All this to tell you that greatly depends on what you will be using it for.
Other things to consider is if you want to ad the advantage of fairings for wind protection or not.
I would start with the budget first and see what are the choices available.
then see what you really want it for and go from there.
Edit: I have now the Pan and the Shadow together